Effects of fenofibrate on atherogenic dyslipidemia in hypertriglyceridemic subjects
نویسندگان
چکیده
منابع مشابه
[Antiplatelet effects of micronized fenofibrate in subjects with dyslipidemia].
INTRODUCTION Fibrates produce additional actions such as reduction of inflammatory state, insulin resistance and activation of blood coagulation, along with stimulation of fibrinolysis. It is not known whether fibrates can attenuate platelet activation. OBJECTIVES Evaluation of antiplatelet effects of fenofibrate in dyslipidemic subjects. PATIENTS AND METHODS In 20 patients (15 males, 5 fem...
متن کاملFenofibrate reduces low density lipoprotein catabolism in hypertriglyceridemic subjects.
This study examines the kinetic basis for the increment in plasma low density lipoprotein (LDL) levels that accompanies the fenofibrate treatment of severely hypertriglyceridemic (HTG) patients. Seven HTG men with a mean plasma triglyceride level of 1470 mg/dl were treated for 6 weeks. During treatment, their plasma triglyceride level fell by 77% and their cholesterol level by 41%. The fall in ...
متن کاملAdditive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patients.
OBJECTIVE Mechanisms underlying fibric acid and angiotensin II type 1 receptor blocker therapies differ. Signaling from peroxisome proliferator-activated receptor alpha may cross-talk with the angiotensin II system. We investigated vascular and metabolic responses to these therapies either alone or in combination in hypertriglyceridemic hypertensive patients. RESEARCH DESIGN AND METHODS This ...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2006
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960290609